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HLA-A

From studying HLA antibodies in transplantation to immune cell populations in infections and cancer

We have selected a highly representative set of functionally intact HLA-A alleles that include allele frequencies, transplant frequencies, and ethnicity coverage for your immunological research.

BROWSE ALL sHLA-A ALLELES
HLA-A proteins
Popular Products
HLA–A*02:01
Most popular allele studied among HLA Scientists
HLA–A*01:01
Among the top A alleles found in the human population
HLA–A*03:01
Prevalent A allele in most populations worldwide
HLA–A*11:01
One of the highest "A" frequencies identified among humans
HLA–A*23:01
Common allele found in cross-reactive antibody studies with A*24:02
HLA–A*24:02
One of the most common alleles found in the world population
HLA–A*31:01
Reported to be associated with carbamazepine -induced hypersensitivity reactions in multiple populations
HLA–A*68:01
Highly cross-reactive in serological testing with A*02:01
Available HLA-A alleles
EXPAND HLA-A MAP

HLA-A Allele Map

Download our list of HLA-A alleles to view all available sHLA proteins as well as products in development.

Download HLA-A Alleles

Featured Assays

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General ImmunoAssays

Soluble HLAs are extremely well suited as antigens in solid phase immunoassays for the detection and characterization of HLA-specific antibodies. Because of their antigenic integrity, they provide increased accuracy and specificity.
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Bead-based ImmunoAssays

Biotin-labeled sHLA molecules are easily immobilized on any streptavidin-coated bead in immunoassays to measure antibody analytes. Fluorescent imaging is used to measure the amount of captured antibody.
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Cell-Based ImmunoAssays

Biotin-labeled sHLA proteins coupled with a fluorescently labeled streptavidin conjugate are very sensitive detectors in ELISpot assays to profile the antibody specificities of i.e. HLA-specific B cells.
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Flow Cytometry/Cell Sorting

Immune cells stained with a biotin-labeled sHLA molecule in combination with a fluorescently labeled streptavidin conjugate of choice can be analyzed by flow cytometry or sorted according to their antigenic type.

Resources

Soluble HLA Technology

Learn more about our sHLA Technology and how it can improve the quality and speed of your science

HLA APPLICATIONS

Explore the landscape of HLA applications in the fields of transplantation, autoimmunity, cancer and infectious diseases and find new ways to improve your research

SOLUBLE HLA PUBLICATIONS

Read more about our publications and discover new resources and ideas to support your endeavors

Frequently Asked Questions

What is a soluble HLA molecule?

Soluble HLA molecules are recombinant proteins that have been technologically modified by removing the interfering transmembrane domain so they can be easily worked with.

How is soluble HLA different from natural HLA?

Soluble HLA differ from natural membrane-bound HLA only in one aspect, they have no transmembrane and cytoplasmic tail. The remainder of the molecule is equally antigenic for antibody recognition and loaded with endogenous peptides.

What does VLDL stand for?

VLDL stands for very low-density lipoprotein and herein defines a 10 amino acid stretch [SVVSTDDDLA] of the VLDL receptor that can be utilized as purification tag for affinity purification.

Browse All FAQS

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HLA-C Proteins

Discover a selection of over 20 HLA-C alleles, the dominant ligand for KIR on NK cells for your immunological research

Peptide Validation and Screening Services

Competition-based HLA peptide binding assays for the validation and screening of putative T cell epitopes